Aside

Contact Info

Skills

Bayesian statistical modelling

Data visualization

iOS, macOS, and watchOS app development

Programming Languages

Main

Joshua Cook

Graduent Student Researcher

As an undergrad, I studied the parasite Toxoplasma gondii, and I currently study cancer genetics using bioinformatics with a specific focus on Bayesian methods. I am looking to once again switch disciplines but continue utilizing and improving my Bayesian statistical analysis skills.

Education

Harvard Medical School

Biomedical and Biological Sciences PhD. program

Boston, MA

2017

Studying cancer genetics with bioinformatics and statistical modeling.

University of California, Irvine

B.S. in Biochemistry and Molecular Biology & B.S. in Chemistry

Irvine, CA

2013 - 2017

Magna Cum Laude with a cumulative GPA of 3.94 and Honors in Biology.

Research Experience

Graduate Research Assistant

Beijing Institute of Genomics, Chinese Academy of Sciences

Beijing, China

2011 - 2014

  • Performed computational biology research towards understanding regulation of alternative splicing in human and mouse transcriptome.
  • Found EGFR pathway related mutations, aimed to understand the impacts of cancer mutations on EGFR signaling pathway.

Bioinformatican

My Health Gene Technology Co., Ltd.

Beijing, China

2015 - 2016

  • Investigated how cancer cells spread to other parts of the body at the single cell level.

Visiting Scientist

University of Alabama at Birmingham

AL, USA

2016 - 2018

  • Investigated the role of mitochondria in development of cancer.
  • Investigated the evolution of genome architecture and its role in important evolutionary events.
  • Detected thrombotic thrombocytopenic purpura related mutations in mutiple patients’ blood genome.

Professional Experience

Data Scientist, intern

SupStat Inc.

Beijing, China

2014

  • Taught R language to beginners.
  • Wrote Shiny app demos.
  • Converted statistical tutorials from SPSS to R language.

Bioinformatician

My Health Gene Technology Co., Ltd.

Beijing, China

2015 - 2016

  • Analyzed whole-exome sequencing data.
  • Wrote analysis pipelines of ChIP-seq, single cell DNA-seq and single cell RNA-seq.
  • Studied tumor metastasis and wrote research reports.
  • Also did case studies to identify the genetic defect causing rare disease.

Teaching Experience

Introduction to R Language for Beginners.

Instructor of R and Data Mining Training Courses at SupStat Inc.

Beijing, China

2014

Computational Biology and Bioinformatics.

Teaching assistant of GBS CB2-201 courses at UAB

AL, USA

2016 - 2017

Selected Publications and Posters

Genetic and epigenetic signals are found predictive to the distribution of intra-individual divergence of alternative splicing.

Poster for 2013 International Conference of Genomics

Qingdao, China

2014

Yu L, Chen B, Zhang Z.

ESCRT-0 complex modulates Rbf mutant cell survival by regulating Rhomboid endosomal trafficking and EGFR signaling.

J Cell Sci. 2016 May 15;129(10):2075-84.

N/A

2016

Sheng Z, Yu L, Zhang T, Pei X, Li X, Zhang Z and Du W.